Compile Data Set for Download or QSAR
Report error Found 5446 of ic50 data for polymerid = 2252,2272,49000493,49000496,50003097
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50051753(1-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111889(1-[3-(3-Chloro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.0770nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111893(1-[3-(3-Chloro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 0.0850nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataIC50: 0.115nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]RTI-55 from dopamine transporter of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50099235(1-[3-(6-Methoxy-naphthalen-2-yl)-8-methyl-8-aza-bi...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50067772(Rhenium complex of 3-(2-Bromo-2,2,2-triformyl-3-me...)
Affinity DataIC50: 0.146nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50099227(1-[3-(6-Ethyl-naphthalen-2-yl)-8-methyl-8-aza-bicy...)
Affinity DataIC50: 0.150nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50021226(CHEMBL296602 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50021226(CHEMBL296602 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50067771(3-(2-Methylsulfanyl-ethylsulfanyl)-propionic acid ...)
Affinity DataIC50: 0.227nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50260904((1R,2R,3S,5S)-2-(2,2-dibromovinyl)-8-methyl-3-p-to...)
Affinity DataIC50: 0.230nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50099225(2-Methyl-1-(8-methyl-3-naphthalen-2-yl-8-aza-bicyc...)
Affinity DataIC50: 0.25nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50055014(7-(3,4-Dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3...)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of [3H]dopamine uptake at the dopamine transporter in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041304(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandPNGBDBM50197470((1S,2S,3S,7R)-methyl 3-(3,4-dichlorophenyl)-7-hydr...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50043303((1-Benzo[b]thiophen-2-yl-cyclohexyl)-butyl-amine |...)
Affinity DataIC50: 0.300nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50102589(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50260905((1R,2R,3S,5S)-3-(4-chlorophenyl)-2-(2,2-dibromovin...)
Affinity DataIC50: 0.320nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50099228(1-[3-(6-Iodo-naphthalen-2-yl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.350nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataIC50: 0.360nMAssay Description:Displacement of [3H]mazindol from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataIC50: 0.360nMAssay Description:Displacement of [3H]mazindol from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50035734([3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 0.370nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50035734([3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50334460(RTI-229 | CHEMBL1643896 | ((1R,2S,3S,5S)-3-(4-iodo...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111888(1-[3-(3-Fluoro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.380nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50099233(1-[3-(6-Isopropyl-naphthalen-2-yl)-8-methyl-8-aza-...)
Affinity DataIC50: 0.390nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandPNGBDBM50197437((1R,2S,3R)-methyl 3-(3,4-dichlorophenyl)-8-methyl-...)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50: 0.400nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 0.430nMAssay Description:Compound was evaluated for the inhibition of [3H]WIN-35428l binding to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50: 0.430nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 0.430nMAssay Description:Displacement of [125I]RTI-55 dopamine transporter binding in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50099223(1-[3-(7-Iodo-naphthalen-2-yl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.450nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50125902((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50: 0.460nMAssay Description:Binding affinity towards dopamine transporter in rat striatum using [3H]WIN-35 428 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50138651(3-(4-Chloro-phenyl)-2-(3-ethyl-isoxazol-5-yl)-8-me...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50090975(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50138654(3-(4-Chloro-phenyl)-8-methyl-2-(3-methyl-isoxazol-...)
Affinity DataIC50: 0.590nMAssay Description:Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50052158((2S,5R)-3-(4-Chloro-phenyl)-8-methyl-2-(3-methyl-i...)
Affinity DataIC50: 0.590nMAssay Description:Binding affinity against Dopamine transporter using [3H]WIN-35 428 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50054754(1-(2-Benzhydryloxy-ethyl)-4-((E)-3-phenyl-allyl)-[...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of dopamine (DA) reuptake using cloned human dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50035747(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50: 0.610nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50046732((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...)
Affinity DataIC50: 0.620nMAssay Description:In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50046732((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 5446 total ) | Next | Last >>
Jump to: