Compile Data Set for Download or QSAR
Report error Found 1454 of ic50 data for polymerid = 2056,6814
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632580(CHEMBL5437070)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human Jurkat cells incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50408828(CHEMBL5270588)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of STAT3 (unknown origin) DNA binding activity by EMSAMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588528(CHEMBL5209107)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632576(CHEMBL5439447)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human KIT225 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632571(CHEMBL5405538)
Affinity DataIC50: 7nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human KIT225 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632570(CHEMBL5433451)
Affinity DataIC50: 9nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human KIT225 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of STAT3 phosphorylation in HEL 92.1.7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588530(CHEMBL5201151)
Affinity DataIC50: 13nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620353(CHEMBL5404765)
Affinity DataIC50: 13nMAssay Description:Inhibition of IL-6 stimulated STAT3 phosphorylation in HEK-Blue IL-6 cells incubated for 20 to 24 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50519537(CHEMBL4469750)
Affinity DataIC50: 13nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human KIT225 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530395(CHEMBL4444178)
Affinity DataIC50: 15nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human KIT225 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620343(CHEMBL5395308)
Affinity DataIC50: 17nMAssay Description:Inhibition of IL-6 stimulated STAT3 phosphorylation in HEK-Blue IL-6 cells incubated for 20 to 24 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)
Affinity DataIC50: 18nMAssay Description:Inhibition of IFN-alpha induced STAT3 phosphorylation in human PBMC preincubated with compound for 30 mins followed by IFN-alpha stimulation and meas...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588531(CHEMBL5171007)
Affinity DataIC50: 20nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021656(LY-3009104 | INCB-028050 | BARICITINIB | US1011290...)
Affinity DataIC50: 20nMAssay Description:Inhibition of IL-23 stimulated STAT3 production in human naive T cell preincubated with compound for 10 to 15 mins followed by IL-23 stimulation and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588507(CHEMBL5178622)
Affinity DataIC50: 22nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50335201(5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Stat3 phosphorylation in human SET2 cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590873(CHEMBL5176684)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588526(CHEMBL5189135)
Affinity DataIC50: 28nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM515659(US11053219, Example 28 | BDBM515661 | US11053219, ...)
Affinity DataIC50: 28nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human KIT225 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632573(CHEMBL5428659)
Affinity DataIC50: 29nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human KIT225 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588514(CHEMBL5184385)
Affinity DataIC50: 31nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590921(CHEMBL5176948)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)
Affinity DataIC50: 33nMAssay Description:Inhibition of IL-6 induced STAT3 phosphorylation in human PBMC preincubated with compound for 30 mins followed by IL-6 stimulation and measured after...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612060(CHEMBL5279856)
Affinity DataIC50: 35nMAssay Description:Inhibition of STAT3 phosphorylation a in human MOLM16 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588527(CHEMBL5201419)
Affinity DataIC50: 36nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590882(CHEMBL5182844)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588529(CHEMBL5209399)
Affinity DataIC50: 38nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620351(CHEMBL5405344)
Affinity DataIC50: 38nMAssay Description:Inhibition of IL-6 stimulated STAT3 phosphorylation in HEK-Blue IL-6 cells incubated for 20 to 24 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588524(CHEMBL5205645)
Affinity DataIC50: 39nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590895(CHEMBL5185530)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590914(CHEMBL5199234)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588518(CHEMBL5175035)
Affinity DataIC50: 40nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)
Affinity DataIC50: 40nMAssay Description:Inhibition of IL-2 induced STAT3 phosphorylation in human PBMC preincubated with compound for 30 mins followed by IL-2 stimulation and measured after...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021656(LY-3009104 | INCB-028050 | BARICITINIB | US1011290...)
Affinity DataIC50: 44nMAssay Description:Inhibition of IL-6 stimulated STAT3 phosphorylation in human PBMC preincubated with compound for 10 to 15 mins followed by IL-6 stimulation and measu...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588532(CHEMBL5200170)
Affinity DataIC50: 46nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590923(CHEMBL5196490)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590919(CHEMBL5189947)
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590911(CHEMBL5170615)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590879(CHEMBL5182625)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant STAT3 (127 to 722 residues) transcriptional activity expressed in HEK293T cells in presence of IL-6 by Dual-luciferas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588505(CHEMBL5206754)
Affinity DataIC50: 64nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620347(CHEMBL5434965)
Affinity DataIC50: 65nMAssay Description:Inhibition of IL-6 stimulated STAT3 phosphorylation in HEK-Blue IL-6 cells incubated for 20 to 24 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632572(CHEMBL5424441)
Affinity DataIC50: 65nMAssay Description:Inhibition of IL-23 induced STAT3 phosphorylation in human KIT225 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620342(CHEMBL5435482)
Affinity DataIC50: 66nMAssay Description:Inhibition of IL-6 stimulated STAT3 phosphorylation in HEK-Blue IL-6 cells incubated for 20 to 24 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50569071(CHEMBL4846365)
Affinity DataIC50: 67nMAssay Description:Inhibition of IL-6 induced STAT3 transcriptional activity in human HepG2 cells incubated for 1 hr followed by stimulation with IL-6 for 5.5 hrs by lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50300648(4-(3-((S)-1-((cis)-2-((S)-5-amino-1-(benzylamino)-...)
Affinity DataIC50: 68nMAssay Description:Inhibition of Stat3 SH2 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50300657(4-(3-((S)-1-((cis)-2-((2R,3S)-6-amino-2-(benzyloxy...)
Affinity DataIC50: 69nMAssay Description:Inhibition of Stat3 SH2 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50300658(4-((E)-3-((S)-1-((1R,2S,5S)-2-(2-(benzyloxy)ethylc...)
Affinity DataIC50: 69nMAssay Description:Inhibition of Stat3 SH2 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620344(CHEMBL5412619)
Affinity DataIC50: 69nMAssay Description:Inhibition of IL-6 stimulated STAT3 phosphorylation in HEK-Blue IL-6 cells incubated for 20 to 24 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
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