Compile Data Set for Download or QSAR
Report error Found 6944 of ic50 data for polymerid = 1595,3881,50001918
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605778(CHEMBL5186216)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM125994(US8772288, 19)
Affinity DataIC50: 0.0400nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605750(CHEMBL5172781)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605782(CHEMBL5174953)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50352566(CHEMBL1825148 | US8772288, 23)
Affinity DataIC50: 0.0600nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605751(CHEMBL5180443)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50356004(CHEMBL1911339)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM16015(CHEMBL252967 | N-cyclopropyl-4-[4-(3,4-dichlorophe...)
Affinity DataIC50: 0.0780nMpH: 7.0 T: 2°CAssay Description:HTRF relies on fluorescence resonance energy transfer (FRET) between the donor, a europium cryptate (EuK), and the acceptor, the light harvesting pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50175745(7-(1-tert-butylpiperidin-4-yl)-1-(2,6-dichlorophen...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of wild type p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605749(CHEMBL5206397)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50352565(CHEMBL1825149)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50352566(CHEMBL1825148 | US8772288, 23)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122386(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122387(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122385(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50175747(7-(1-tert-butylpiperidin-4-yl)-5-(2-chlorophenyl)-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of P38 alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM15459(4-{1-methyl-2-piperidin-4-yl-4-[3-(trifluoromethyl...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of wild type p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50241077(CHEMBL4060815)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122385(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article

TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122386(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article

TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122387(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article

TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605747(CHEMBL5173417)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605753(CHEMBL5200224)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605781(CHEMBL5202475)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122385(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122386(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122387(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50375790(CHEMBL270004)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandPNGBDBM15240(4-[1-methyl-2-(piperidin-4-yl)-4-[3-(trifluorometh...)
Affinity DataIC50: 0.130nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122390(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122390(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article

TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50357914(CHEMBL1916528)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human p38alpha MAP kinase after 1 hr by FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122390(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50175745(7-(1-tert-butylpiperidin-4-yl)-1-(2,6-dichlorophen...)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of P38 alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50375797(CHEMBL269792)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50356003(CHEMBL1911338)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50560252(CHEMBL4764056)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandPNGBDBM17060(CHEMBL319556 | 1-(2,6-dichlorophenyl)-5-(2,4-diflu...)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandPNGBDBM17061(1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-[1...)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50348312(CHEMBL1800222 | US8772288, 12)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM125218(US8772481, 16)
Affinity DataIC50: 0.200nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122384(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piper...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50122379(7-(1-tert-Butyl-piperidin-4-yl)-5-(2-chloro-4-fluo...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM17060(CHEMBL319556 | 1-(2,6-dichlorophenyl)-5-(2,4-diflu...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50241013(CHEMBL4066023)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50241058(CHEMBL4104440)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50241059(CHEMBL4069496)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50425360(CHEMBL2316207)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50241078(CHEMBL4073561)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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