Compile Data Set for Download or QSAR
Report error Found 157 of ic50 data for polymerid = 1568
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193234({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50138156(Biphenyl-4-carboxylic acid {1-[(3-aminomethyl-phen...)
Affinity DataIC50: 130nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447515(CHEMBL3115901)
Affinity DataIC50: 130nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193230({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-2,3-di...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447516(CHEMBL3115900)
Affinity DataIC50: 260nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193224(((R)-1-{[(S)-(4-carbamimidoyl-benzylcarbamoyl)-ind...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193229({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-2,3-di...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447528(CHEMBL3115904)
Affinity DataIC50: 470nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447523(CHEMBL3115897)
Affinity DataIC50: 670nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193242({(R)-1-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-...)
Affinity DataIC50: 710nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193241({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-...)
Affinity DataIC50: 750nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193240({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)
Affinity DataIC50: 820nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 870nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447517(CHEMBL3115894)
Affinity DataIC50: 920nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447521(CHEMBL3115899)
Affinity DataIC50: 980nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193235({(R)-1-[6-(4-carbamimidoyl-benzylcarbamoyl)-6,7-di...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447514(CHEMBL3115903)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447522(CHEMBL3115898)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193228({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193235({(R)-1-[6-(4-carbamimidoyl-benzylcarbamoyl)-6,7-di...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447525(CHEMBL3115893)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447527(CHEMBL3115905)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193232({(R)-1-[6-(4-carbamimidoyl-benzylcarbamoyl)-6,7-di...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193222(2-{[(1R)-1-[(2-{[(4-carbamimidoylphenyl)methyl]car...)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447519(CHEMBL3115906)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447524(CHEMBL3115896)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447518(CHEMBL3115892)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50114455(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 3.70E+3nMAssay Description:Tested in vitro for the inhibitory activity against activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447520(CHEMBL3115902)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193238({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-...)
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50447526(CHEMBL3115907)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50124984((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against activated protein C (aPC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50106057(3-Carbamimidoyl-N-[(R)-phenyl-(2'-sulfamoyl-biphen...)
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibitory activity against activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193237({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-...)
Affinity DataIC50: 9.08E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193239({(R)-1-[2-(4-carbamimidoyl-benzylcarbamoyl)-2,3-di...)
Affinity DataIC50: 9.28E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140386(2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140413(2-(3-Fluoro-naphthalen-2-yl)-5-trifluoromethyl-2H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against activated protein C was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140416(2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against activated protein C was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140424(2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against activated protein C was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140407(2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against activated protein C was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50142087(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(5-brom...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against activated protein C was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140367(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140380(2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140370(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50140360(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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