Compile Data Set for Download or QSAR
Report error Found 58 of ic50 data for polymerid = 1541
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50092365((R)-3-Benzyl-1-(3H-imidazol-4-ylmethyl)-4-(thiophe...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human H-rasMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50092365((R)-3-Benzyl-1-(3H-imidazol-4-ylmethyl)-4-(thiophe...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of HRAS (unknown origin) farnesylationMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50063453(1-[4-((S)-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclo...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of H-Ras (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50089960(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50089961(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1-...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50089969(5-[Bis-(2-chloro-ethyl)-amino]-benzofuran-2-carbox...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50089962(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-be...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50089967(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50089978(5-[Bis-(2-chloro-ethyl)-amino]-1H-indole-2-carboxy...)
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50089971(5-[Bis-(2-chloro-ethyl)-amino]-1-methyl-1H-indole-...)
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060139([(S)-1-((4-Benzyloxy-benzyl)-{[(1-phenyl-cyclobuty...)
Affinity DataIC50: 88nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50601398(CHEMBL5174384)
Affinity DataIC50: 100nMAssay Description:Inhibition of [35S]methionine labelled HRAS in rat Rat1 cells by immunoprecipitation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50601400(CHEMBL5171806)
Affinity DataIC50: 100nMAssay Description:Inhibition of HRAS (unknown origin) transfected in BALB/c nude mouse incubated for 3 days measured by immunoblot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060146([(S)-1-((4-Benzyloxy-benzyl)-{[(1-phenyl-cycloprop...)
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060141([(S)-1-{(4-Benzyloxy-benzyl)-[(2-methyl-2-phenyl-p...)
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060140([(S)-1-{(4-Benzyloxy-benzyl)-[(2-cyano-2-phenyl-et...)
Affinity DataIC50: 190nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50055659(CHEMBL11252 | 2N-[5-(3-amino-3-iminopropylcarbamoy...)
Affinity DataIC50: 200nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060145([(S)-1-{(4-Benzyloxy-benzyl)-[((S)-2-phenyl-propyl...)
Affinity DataIC50: 300nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060138([(S)-1-{(4-Benzyloxy-benzyl)-[(2-phenyl-propylcarb...)
Affinity DataIC50: 310nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060142([(S)-1-((4-Benzyloxy-benzyl)-{[(1-phenyl-cyclopent...)
Affinity DataIC50: 330nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060149([(S)-1-{(4-Benzyloxy-benzyl)-[(2-phenyl-butylcarba...)
Affinity DataIC50: 400nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060150([(S)-1-{(4-Benzyloxy-benzyl)-[((R)-2-phenyl-propyl...)
Affinity DataIC50: 570nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060144([(S)-1-{(4-Benzyloxy-benzyl)-[((R)-1-methyl-2-phen...)
Affinity DataIC50: 710nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287960(1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060152([(S)-1-{(4-Benzyloxy-benzyl)-[(2-ethyl-2-phenyl-bu...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060148([(S)-1-{(4-Benzyloxy-benzyl)-[(2-phenyl-pentylcarb...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287951(3-[(3aS,4R,6R,6aR)-6-(4-Chloro-6-methoxy-3-methyl-...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50478506(Ophirapstanol Trisulfate)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human recombinant p21RAS by GDPX assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287961((E)-5-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50059857([(S)-1-[(4-Benzyloxy-benzyl)-(phenethylcarbamoyl-m...)
Affinity DataIC50: 4.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287943((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50: 4.70E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287946(1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50060143([(S)-1-{(4-Benzyloxy-benzyl)-[((S)-1-methyl-2-phen...)
Affinity DataIC50: 6.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287963([(2S,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyrazolo[3...)
Affinity DataIC50: 6.70E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287959((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287955((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50: 7.40E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287958([(2S,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyrazolo[3...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50072339(Benzodiazepine-Distamycin Hybrid | CHEMBL102341)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Ha-ras polymerase-chain reaction productMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287945(5-(4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]q...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287944((E)-3-[(2S,3S,4R,5R)-5-(4-Chloro-6-methoxy-3-methy...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287953(5-(4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]q...)
Affinity DataIC50: 1.05E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287962([(2S,6R)-4-Benzenesulfonyl-6-(4-chloro-6-methoxy-3...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287949(1-[(2R,6S)-4-Benzenesulfonyl-6-(tert-butyl-dimethy...)
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287948([(2S,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyrazolo[3...)
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50059879([(S)-1-{(4-Benzyloxy-benzyl)-[(2-benzyloxy-ethylca...)
Affinity DataIC50: 1.43E+4nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287956(Benzoic acid (3aR,4R,6R,6aR)-6-(4-chloro-6-methoxy...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287947((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50: 1.60E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50610922(CHEMBL5209443)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged HRAS (1 to 166 residues) (unknown origin) assessed as inhibition of mSOS1 mediated nucleotide exchange by [35S]GTPgammaS bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287952(N-{4-[(2S,6R)-2-(tert-Butyl-dimethyl-silanyloxymet...)
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGTPase HRas(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50287954((E)-3-[(2S,5R)-5-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50: 3.50E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article

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