Compile Data Set for Download or QSAR
Report error Found 386 of ic50 data for polymerid = 1346,50006730
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119052(Biotinylated E-76 peptide analogue | CHEMBL269354)
Affinity DataIC50: 1nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119057(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50: 1nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119050(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119049(Biotinylated E-76 peptide analogue | CHEMBL439285)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50167837(3-Amino-N-((R)-sec-butyl)-5-{1-[(4-carbamimidoyl-b...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119048(Biotinylated E-76 peptide analogue | CHEMBL437872)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50127212(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50127214(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50127212(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50127214(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119057(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119055(Biotinylated E-76 peptide analogue | CHEMBL414777)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50127213(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237234...)
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119057(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50127213(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237234...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119056(Biotinylated E-76 peptide analogue | CHEMBL439444)
Affinity DataIC50: 4nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50520865(CHEMBL4469752)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM13592(2-{2-[(4-carbamimidoylphenyl)carbamoyl]-6-methoxyp...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50167830(3-amino-N-[(2R)-butan-2-yl]-5-[1-({[(4-carbamimido...)
Affinity DataIC50: 6.20nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50439474(CHEMBL2417906)
Affinity DataIC50: 7nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31501(substituted biphenyl derivative, 36ao)
Affinity DataIC50: 8nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50439477(CHEMBL2417903)
Affinity DataIC50: 9nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31462(substituted biphenyl derivative, 36b)
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31468(substituted biphenyl derivative, 36h)
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31488(substituted biphenyl derivative, 36ab)
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31497(substituted biphenyl derivative, 36ak)
Affinity DataIC50: 9nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31499(substituted biphenyl derivative, 36am)
Affinity DataIC50: 9nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119050(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50: 9.20nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50127212(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50: 9.20nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50167833(3-amino-N-[(2R)-butan-2-yl]-5-(1-{[({4-carbamimido...)
Affinity DataIC50: 9.40nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119050(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50: 9.70nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31486(substituted biphenyl derivative, 36z)
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31487(substituted biphenyl derivative, 36aa)
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119047(Biotinylated E-76 peptide analogue | CHEMBL441926)
Affinity DataIC50: 10nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50439475(CHEMBL2417905)
Affinity DataIC50: 11nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50439487(CHEMBL2417893)
Affinity DataIC50: 11nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31470(substituted biphenyl derivative, 36j)
Affinity DataIC50: 11nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31489(substituted biphenyl derivative, 36ac)
Affinity DataIC50: 11nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31493(substituted biphenyl derivative, 36ag)
Affinity DataIC50: 11nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119050(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50520866(CHEMBL4469308)
Affinity DataIC50: 11nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31474(substituted biphenyl derivative, 36n)
Affinity DataIC50: 12nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119053(Biotinylated E-76 peptide analogue | CHEMBL415402)
Affinity DataIC50: 12nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50167836(3-amino-N-[(2R)-butan-2-yl]-5-(1-{[({4-carbamimido...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50520867(CHEMBL4441346)
Affinity DataIC50: 12nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50439473(CHEMBL2417907)
Affinity DataIC50: 13nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50439486(CHEMBL2417894)
Affinity DataIC50: 13nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM31467(substituted biphenyl derivative, 36g)
Affinity DataIC50: 13nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119054(Biotinylated E-76 peptide analogue | CHEMBL429011)
Affinity DataIC50: 13nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50119059(Biotinylated E-76 peptide analogue | CHEMBL410836)
Affinity DataIC50: 13nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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