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TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619701(CHEMBL1575436)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 2.90E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619701(CHEMBL1575436)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human MKP5 catalytic domain (320 to 467 residues) expressed in Escherichia coli BL21 (DE3) cells by MST assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619703(CHEMBL5418996)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619709(CHEMBL5393799)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.70E+3nMpH: 7.0Assay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619702(CHEMBL5420188)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619710(CHEMBL5427332)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619704(CHEMBL5396788)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619711(CHEMBL5434976)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619707(CHEMBL5428133)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619712(CHEMBL5416499)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619719(CHEMBL5427448)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619721(CHEMBL5399164)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619705(CHEMBL5418920)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619715(CHEMBL5405382)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619720(CHEMBL5405398)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619718(CHEMBL5419280)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619706(CHEMBL5419382)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619708(CHEMBL5405183)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619713(CHEMBL5404337)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619714(CHEMBL5420697)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619716(CHEMBL5434241)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619717(CHEMBL5397402)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed