Compile Data Set for Download or QSAR
Report error Found 16 of ic50 data for polymerid = 11101
TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50160879(US9505736, (1S,2S,3S)-1-Fluoro-2-(4-(5- fluoropyri...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257503(US9505736, (1S,2S,3S)-1-Fluoro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50: 20nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257508(US9505736, (1S,2S,3S)-2-(4-(2-Cyclopropyloxazol- 5...)
Affinity DataIC50: 20nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50160874(US9505736, (1S,2S,3S)-2-(4-(5- (Difluoromethoxy)py...)
Affinity DataIC50: 40nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50161831(US9505736, (1S,2S,3S)-1-Fluoro-N-hydroxy-2-phenyl-...)
Affinity DataIC50: 40nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257501(US9505736, (1S,2S,3S)-2-(4-Bromophenyl)-1- fluoro-...)
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257509(US9505736, (1S,2R,3S)-1-Fluoro-2-(2-(4- fluorophen...)
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50155803(US9505736, (1S,2S,3S)-1-Chloro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50: 110nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257511(US9505736, (1R,2R,3R)-1-Fluoro-2-(4-(5- fluoropyri...)
Affinity DataIC50: 410nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257505(US9505736, (1R,2R,3R)-1-Fluoro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50: 1.43E+3nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257504(US9505736, (1R,2R,3R)-1-Chloro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50: 1.58E+3nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257507(US9505736, (1R,2S,3S)-2-(4-(2-Cyclopropyloxazol- 5...)
Affinity DataIC50: 4.65E+3nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257502(US9505736, (1R,2S,3S)-2-(8-Chloro-2,3- dihydrobenz...)
Affinity DataIC50: 6.47E+3nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257510(US9505736, (1R,2R,3R)-1-Fluoro-N-hydroxy-2-phenyl-...)
Affinity DataIC50: 6.87E+3nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257506(US9505736, (1R,2R,3R)-2-(4-(5- (Difluoromethoxy)py...)
Affinity DataIC50: 2.60E+4nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257512(US9505736, (1R,2S,3S)-2-(2-Cyclopropylpyridin-4- y...)
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails
US Patent