Compile Data Set for Download or QSAR
Report error Found 3154 of ic50 data for polymerid = 111
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50072583((2R,3S)-2,N*1*-Dihydroxy-N*4*-[(S)-1-(1H-indole-3-...)
Affinity DataIC50: 0.260nMAssay Description:In vitro inhibitory activity against matrix metalloprotease 1 isolated from the culture medium of human skin fibroblasts induced with PMAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063915((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-methyl-N*1*-[(S)...)
Affinity DataIC50: 0.300nMAssay Description:Activity against Matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 0.400nMAssay Description:Activity against Matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50254802(CHEMBL4088630)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human interstitial recombinant N-terminal MMP1 expressed in Escherichia coli BL21(DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082543((S)-4-(4-bromo-2-methylphenylsulfonyl)-N-hydroxy-2...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of recombinant human MMP1 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082541((S)-4-(4-bromophenylsulfonyl)-N-hydroxy-2,2-dimeth...)
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.780nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082545((S)-N-hydroxy-4-(4-methoxyphenylsulfonyl)-2,2-dime...)
Affinity DataIC50: 0.800nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082545((S)-N-hydroxy-4-(4-methoxyphenylsulfonyl)-2,2-dime...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human interstitial recombinant N-terminal MMP1 expressed in Escherichia coli BL21(DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as sub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082991((2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50: 0.880nMAssay Description:Inhibitory activity against MMP-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of human Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50181002((S)-N-hydroxy-2,2-dimethyl-4-(4-(prop-2-ynyloxy)ph...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082534((S)-2,2-Dimethyl-4-(5-pyridin-2-yl-thiophene-2-sul...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082550((S)-4-(4-Methoxy-benzenesulfonyl)-6-methoxymethoxy...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50102750(CHEMBL3359091)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50622040(CHEMBL5394834)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50622041(CHEMBL4859817)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50622043(CHEMBL5426756)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50622044(CHEMBL5413816)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50622045(CHEMBL5412452)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50622047(CHEMBL5400294)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity against matrix metalloprotease 1 isolated from the culture medium of human skin fibroblasts induced with PMAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50072566((2R,3S)-2-Allyl-N*4*-[(S)-1-benzyl-2-(1H-indol-3-y...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity against matrix metalloprotease 1 isolated from the culture medium of human skin fibroblasts induced with PMAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082945((2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against MMP-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50072566((2R,3S)-2-Allyl-N*4*-[(S)-1-benzyl-2-(1H-indol-3-y...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PMA-induced human skin fibroblast derived MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50562069(CHEMBL4785595)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PMA-induced human skin fibroblast derived MMP1 by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibitory activity against matrix metalloprotease 1 isolated from the culture medium of human skin fibroblasts induced with PMAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50072563((2R,3S)-2-Allyl-N*1*-hydroxy-N*4*-[(S)-1-(1H-indol...)
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibitory activity against matrix metalloprotease 1 isolated from the culture medium of human skin fibroblasts induced with PMAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082957((2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against MMP-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50098923((3R,9aS)-2-(4-Methoxy-benzenesulfonyl)-5-oxo-octah...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082552((S)-4-(4-Bromo-benzenesulfonyl)-2,2-dimethyl-1,1-d...)
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50070457((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-methyl-N*1*-((S)...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082963((2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against MMP-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50175534(N-Hydroxy-3-(7-oxo-7,8-dihydro-6H-quinolizine-4-su...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50175542(7-Oxo-7,8-dihydro-6H-quinolizine-4-carboxylic acid...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50175564(N-Hydroxy-2-(7-oxo-7,8-dihydro-6H-quinolizine-4-su...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50146634(N*1*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 1.5nMAssay Description:Activity against Matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50082980((2R,3S)-2-(Benzenesulfonyl-methyl-amino)-N*4*-((S)...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against MMP-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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