Compile Data Set for Download or QSAR
Report error Found 910 of ic50 data for polymerid = 1068,50001377
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50380208(CHEMBL2011408)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50168219(CHEMBL3805209)
Affinity DataIC50: 0.0240nMAssay Description:Inhibition of estrone sulfatase (unknown origin) transfected in HEK293 cells using E1S as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.0300nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50121196(CHEMBL3622029)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of STS activity in human JEG-3 cells by liquid scintillation spectrometry in presence of [6,7-3H]estrone3-sulfateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50168217(CHEMBL3806018)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of estrone sulfatase (unknown origin) transfected in HEK293 cells using E1S as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50545255(CHEMBL4643348)
Affinity DataIC50: 0.0400nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50118551(Sulfamic acid 2-tert-butyl-4-oxo-4H-chromen-6-yl e...)
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50168219(CHEMBL3805209)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Rat)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of estrone sulfatase in homogeneous rat mammary tumorsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50134329(Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8...)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of STS in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50134329(Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8...)
Affinity DataIC50: 0.0650nMAssay Description:Inhibitory activity against estrone sulfatase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50134329(Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8...)
Affinity DataIC50: 0.0650nMAssay Description:Inhibitory concentration required to inhibit the enzyme estrone sulfatase was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50134329(Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8...)
Affinity DataIC50: 0.0650nMAssay Description:Tested for the inhibitory activity against Estrone SulfataseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50134329(Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8...)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of STS in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50590842(CHEMBL5202760)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of estrone sulfatase in human MCF7 cells assessed as inhibition of [3H]estrone and [3H]estradiol formation using [3H]estrone sulfate as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50134329(Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8...)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of STS in human MCF7 cells assessed as reduction in [3H]estradiol and [3H]estrone formation using [3H]estrone sulfate as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50118567(Sulfamic acid 2-nonyl-4-oxo-4H-chromen-6-yl ester ...)
Affinity DataIC50: 0.0890nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50380223(CHEMBL2011422)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of placental microsomal estrone sulfatase (unknown origin) using [6,7-3H]E1S as substrate incubated for 1 hr by scintillation spectrometri...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50380223(CHEMBL2011422)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of steroid sulfatase in human placental microsomes using [3H]E1S as substrate after 30 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50380216(CHEMBL364332)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of estrone sulfatase in human MCF7 cell microsomesMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50337122(2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazo...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50136297(Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxa...)
Affinity DataIC50: 0.150nMAssay Description:Inhibitory activity against human steroid sulfatase in sebocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50136297(Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxa...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of estrone sulfatase in human sebocytes using DHEAS as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human placental estrone sulfatase expressed in HEK293 cells using [3H]E1S as substrate incubated for 2 hrs by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.150nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50136297(Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxa...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50136297(Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxa...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50604012(CHEMBL5199004)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50118560(Sulfamic acid 2-adamantan-1-yl-4-oxo-4H-thiochrome...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of recombinant human estrone sulfatase using 4-methylumbelliferyl sulfate as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50118560(Sulfamic acid 2-adamantan-1-yl-4-oxo-4H-thiochrome...)
Affinity DataIC50: 0.340nMAssay Description:Inhibitory activity against purified human steroid sulfatase (STS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50118560(Sulfamic acid 2-adamantan-1-yl-4-oxo-4H-thiochrome...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50118560(Sulfamic acid 2-adamantan-1-yl-4-oxo-4H-thiochrome...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of sulfatase (unknown origin) using 4-MUS as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50118560(Sulfamic acid 2-adamantan-1-yl-4-oxo-4H-thiochrome...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human steroid sulfatase by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50369431(CHEMBL1627878)
Affinity DataIC50: 0.390nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50369431(CHEMBL1627878)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50168259(CHEMBL3806300)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental estrone sulfatase expressed in HEK293 cells using [3H]E1S as substrate incubated for 2 hrs by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50525470(CHEMBL4456330)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50380215(CHEMBL2011415)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50380214(CHEMBL2011414)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50525473(CHEMBL4520442)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50525473(CHEMBL4520442)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of STS (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50136297(Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxa...)
Affinity DataIC50: 0.75nMAssay Description:Inhibitory activity against human steroid sulfatase in fibroblastsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50136297(Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxa...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of estrone sulfatase human keratinocytes using DHEAS as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50136297(Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxa...)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of human STS in keratinocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50136297(Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxa...)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of estrone sulfatase in human MCF7 cells using estrone sulphate as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50380208(CHEMBL2011408)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of steroid sulfatase in human placental microsomes using [3H]E1S as substrate after 30 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50380217(CHEMBL364745)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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