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Report error Found 191 of ic50 data for complexid = 50004167,50017467
TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350239(US10208056, Compound 66)
Affinity DataIC50: 0.191nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350249(US10208056, Compound 76)
Affinity DataIC50: 0.262nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350256(US10208056, Compound 83)
Affinity DataIC50: 0.278nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350253(US10208056, Compound 80)
Affinity DataIC50: 0.314nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350262(US10208056, Compound 89)
Affinity DataIC50: 0.407nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350240(US10208056, Compound 67)
Affinity DataIC50: 0.466nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640341(8-Amino-N-(cyclopropylmethyl)-5-(4- (1-(2-(dimethy...)
Affinity DataIC50: 0.880nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640350(2-(4-(4-(8-amino-3-(azetidine-1- carbonyl)-1,7-nap...)
Affinity DataIC50: 0.960nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540074(US11261184, Example I-021)
Affinity DataIC50: 1nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532287(US11213520, Example I-005)
Affinity DataIC50: 1nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640351(2-(4-(4-(8-amino-3-(azetidine-1- carbonyl)-1,7-nap...)
Affinity DataIC50: 1.01nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640354(8-amino-N-(2-methoxyethyl)-N- methyl-5-(4-(1-(2-(4...)
Affinity DataIC50: 1.07nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM50509567(CHEMBL4455382 | US11213520, Example I-003)
Affinity DataIC50: 1.10nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640345(8-amino-N-cyclopropyl-5-(4-(1-(2-(4- methylpiperaz...)
Affinity DataIC50: 1.10nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640346(8-amino-N-cyclopropyl-5-(4-(1-(2-(2- methoxyethyl)...)
Affinity DataIC50: 1.10nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350252(US10208056, Compound 79)
Affinity DataIC50: 1.11nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640344(8-amino-N-cyclopropyl-5-(4-(1-(2- (dimethylamino)-...)
Affinity DataIC50: 1.11nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540066(US11261184, Example I-013)
Affinity DataIC50: 1.20nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540069(US11261184, Example I-016)
Affinity DataIC50: 1.20nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540071(US11261184, Example I-018)
Affinity DataIC50: 1.20nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532311(US11213520, Example I-007)
Affinity DataIC50: 1.20nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640353(8-amino-5-(4-(1-(2-(dimethylamino)- 2-oxoethyl)-1H...)
Affinity DataIC50: 1.24nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640352((8-amino-5-(4-(1-(2-methoxyethyl)- 1H-pyrazole-4-y...)
Affinity DataIC50: 1.27nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540062(US11261184, Example I-007)
Affinity DataIC50: 1.30nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540063(US11261184, Example I-010)
Affinity DataIC50: 1.30nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540065(US11261184, Example I-012)
Affinity DataIC50: 1.30nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532312(US11213520, Example I-008)
Affinity DataIC50: 1.30nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532314(US11213520, Example I-010)
Affinity DataIC50: 1.30nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350263(US10208056, Compound 90)
Affinity DataIC50: 1.36nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540073(US11261184, Example I-020)
Affinity DataIC50: 1.40nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540077(US11261184, Example I-024)
Affinity DataIC50: 1.40nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532315(US11213520, Example I-011)
Affinity DataIC50: 1.40nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640342(8-amino-N-(cyclopropylmethyl)-5-(4- (1-(2-(4-methy...)
Affinity DataIC50: 1.40nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350211(US10208056, Compound 43)
Affinity DataIC50: 1.41nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350220(US10208056, Compound 52)
Affinity DataIC50: 1.41nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350227(US10208056, Compound 57)
Affinity DataIC50: 1.41nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350257(US10208056, Compound 84)
Affinity DataIC50: 1.41nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350265(US10208056, Compound 92)
Affinity DataIC50: 1.41nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350267(US10208056, Compound 95)
Affinity DataIC50: 1.41nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350268(US10208056, Compound 96)
Affinity DataIC50: 1.41nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350270(US10208056, Compound 105)
Affinity DataIC50: 1.41nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM640349((8-amino-5-(4-(1-(2-methoxyethyl)- 1H-pyrazole-4-y...)
Affinity DataIC50: 1.44nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540064(US11261184, Example I-011)
Affinity DataIC50: 1.5nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540068(US11261184, Example I-015)
Affinity DataIC50: 1.5nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532283(US11213520, Example I-002)
Affinity DataIC50: 1.5nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532321(US11213520, Example I-017)
Affinity DataIC50: 1.5nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540061(US11261184, Example I-006)
Affinity DataIC50: 1.60nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM540078(US11261184, Example I-025)
Affinity DataIC50: 1.60nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532313(US11213520, Example I-009)
Affinity DataIC50: 1.60nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM532320(US11213520, Example I-016)
Affinity DataIC50: 1.60nMAssay Description:Assay-ready plates (ARPs; Proxiplate-384 PLUS, white, PerkinElmer) with compound solution in 100% DMSO are generated on an Access Labcyte Workstation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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