Compile Data Set for Download or QSAR
Report error Found 774 of ic50 data for complexid = 50000882,50004330,50004598,50006071,50013762
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472616(CHEMBL65325)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472618(CHEMBL303092)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472623(CHEMBL294100)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472624(CHEMBL62439)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472627(CHEMBL304489)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472632(CHEMBL65140)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50229761(L-689037 | CHEMBL314337)
Affinity DataIC50: 2nMAssay Description:The compound was tested for inhibitory activity against Prostaglandin G/H synthase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472613(CHEMBL305076)
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472605(CHEMBL64507)
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472612(CHEMBL60496)
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1/2(Mouse)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50229760(WAY-121520 | CHEMBL316184)
Affinity DataIC50: 4nMAssay Description:The compound was tested for inhibitory activity against Prostaglandin G/H synthase in mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012780(Prifelone | CHEMBL8846 | (3,5-Di-tert-butyl-4-hydr...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472615(CHEMBL64813)
Affinity DataIC50: 6.20nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225193(CHEMBL432463)
Affinity DataIC50: 8nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472610(CHEMBL60725)
Affinity DataIC50: 9.10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472622(CHEMBL291543)
Affinity DataIC50: 9.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50331888(5-Chloro-2-oxo-3-(thiophene-2-carbonyl)-2,3-dihydr...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against cyclooxygenase of human platelets was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076666(N-Hydroxy-N-{3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076661(N-{1-Ethyl-3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472631(CHEMBL60738)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50075539(CHEMBL1626563 | CHEMBL17229 | 3-(3,5-Di-tert-butyl...)
Affinity DataIC50: 11nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472619(CHEMBL62990)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472625(CHEMBL62920)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225114(CHEMBL28507)
Affinity DataIC50: 20nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225184(CHEMBL28976)
Affinity DataIC50: 20nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225190(CHEMBL28508)
Affinity DataIC50: 20nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50012860(CHEMBL61422 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-acea...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50: 23nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472603(CHEMBL65330)
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50: 27nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279039(CHEMBL4177185)
Affinity DataIC50: 28nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076659(N-{3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225186(CHEMBL281012)
Affinity DataIC50: 30nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076637(N-Hydroxy-N-{3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076659(N-{3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50223539(CHEMBL33957)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472609(CHEMBL64585)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279036(CHEMBL4162061)
Affinity DataIC50: 33nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012811(CHEMBL266100 | 2,6-Di-tert-butyl-4-(2-thiophen-2-y...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279034(CHEMBL4172740)
Affinity DataIC50: 34nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279035(CHEMBL4165597)
Affinity DataIC50: 38nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225122(CHEMBL29047)
Affinity DataIC50: 40nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076650(N-Hydroxy-N-{3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279023(CHEMBL4176892)
Affinity DataIC50: 41nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279038(CHEMBL4169030)
Affinity DataIC50: 44nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50: 48nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225136(CHEMBL538408)
Affinity DataIC50: 50nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225141(CHEMBL418035)
Affinity DataIC50: 50nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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