Compile Data Set for Download or QSAR
Report error Found 7 of ic50 data for complexid = 50000838
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50528810(CHEMBL4580787)
Affinity DataIC50: 10nMAssay Description:Competitive irreversible inhibition of CDK16/cyclin Y (unknown origin) in presence of Km ATPMore data for this Ligand-Target Pair
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PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 17.2nMAssay Description:Inhibition of human CDK16/cyclin-Y using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human CDK16/cyclin-Y using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50573929(CHEMBL4848734)
Affinity DataIC50: 56nMAssay Description:Inhibition of human CDK16/cyclin-Y using RB protein as substrate incubated for 2 hrs by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50598717(CHEMBL5193702 | US20230348487, Example LS 6-45)
Affinity DataIC50: 135nMAssay Description:Inhibition of human CDK16/cyclin-Y protein-protein complexMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50466210(CHEMBL4281048)
Affinity DataIC50: 292nMAssay Description:Inhibition of recombinant GST-tagged inactive state of human CDK16 (108 to end residues)/cyclin Y (2 to end residues)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50539904(CHEMBL4647764)
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human N-terminal GST-tagged human CDK16 (107 to end residues)/Cyclin Y (2 to end residues) exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed