Compile Data Set for Download or QSAR
Report error Found 50 of ic50 data for complexid = 50000813
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50492928(CHEMBL2414311)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399897(CHEMBL2180942)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126469((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-((R)-1-propyl-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14776(CHEMBL1520 | 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human phosphodiesterase 6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241831(CHEMBL4062273 | US10899756, Compound U | US1062611...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PDE6 (unknown origin) using FAM-cGMP or FAM-cAMP as substrate incubated for 60 mins and measured by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193586(7-benzyl-4-isopropyl-9-methyl-2-phenyl-7H-3,3a,5,7...)
Affinity DataIC50: 62nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126462((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-{(R)-1-[2-(1-m...)
Affinity DataIC50: 125nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126462((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-{(R)-1-[2-(1-m...)
Affinity DataIC50: 125nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126452((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-pyri...)
Affinity DataIC50: 226nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126458((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-((R)-1-benzyl-...)
Affinity DataIC50: 249nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126455((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-pyri...)
Affinity DataIC50: 271nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193569(7-benzyl-4,9-dimethyl-2-pyridin-3-yl-7H-3,3a,5,7,8...)
Affinity DataIC50: 280nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193574(7-benzyl-2-furan-3-yl-4,9-dimethyl-7H-3,3a,5,7,8-p...)
Affinity DataIC50: 330nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193577(3-benzyl-1-ethoxymethyl-6-methyl-9-phenylpyrazolo[...)
Affinity DataIC50: 330nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50428976(CHEMBL2333219)
Affinity DataIC50: 339nMAssay Description:Inhibition of PDE6 (unknown origin) using FAM-cGMP or FAM-cAMP as substrate incubated for 60 mins and measured by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126467((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-{(R)-1-[2-(1H-...)
Affinity DataIC50: 357nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126464((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-pyra...)
Affinity DataIC50: 358nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193578(7-benzyl-4-ethyl-9-methyl-2-phenyl-7H-3,3a,5,7,8-p...)
Affinity DataIC50: 550nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM144390(US8969376, 1.006)
Affinity DataIC50: 561nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193579(7-benzyl-9-methyl-2-phenyl-4-propyl-7H-3,3a,5,7,8-...)
Affinity DataIC50: 610nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126453(3-[(R)-3-((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-1,4-di...)
Affinity DataIC50: 620nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126449(3-[(R)-3-((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-1,4-di...)
Affinity DataIC50: 807nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126456((6R,12aR)-2-[(R)-1-(3-Azetidin-1-yl-3-oxo-propyl)-...)
Affinity DataIC50: 846nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193584(3-benzyl-1-methyl-9-phenylpyrazolo[1',5':1,6]pyrim...)
Affinity DataIC50: 860nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193572(3-benzyl-1-[(dimethylamino)methyl]-6-methyl-9-phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126457((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(3-meth...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50492918(CHEMBL2414316)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126470(3-[(R)-3-((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-1,4-di...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126473((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-(1-benzyl-pipe...)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126468((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-((R)-1-hexyl-p...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human phosphodiesterase 6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193587(7-benzyl-4,9-dimethyl-2-thiophen-3-yl-7H-3,3a,5,7,...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193570(4,7,9-trimethyl-2-phenyl-7H-3,3a,5,7,8-pentaaza-cy...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126466((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-cycl...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126465((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-(2-morpholin-4...)
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50019654(CHEMBL3109802)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50193571(3-benzyl-9-(4-chlorophenyl)-1,6-dimethylpyrazolo[1...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50126460((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-(2-dimethylami...)
Affinity DataIC50: 8.22E+3nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50576279(CHEMBL4871796)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human PDE6More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50512300(CHEMBL4575012)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50512302(CHEMBL4441262)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50141581(4-(3-Chloro-4-methoxy-benzylamino)-7-trifluorometh...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of phosphodiesterase 6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50576275(CHEMBL4873599)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human PDE6More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50497974(CHEMBL3319209)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50542296(CHEMBL4641729)
Affinity DataIC50: 4.38E+4nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50512301(CHEMBL4570812)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed