Compile Data Set for Download or QSAR
Report error Found 219 of ic50 data for complexid = 50000021
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461540(CHEMBL4226033)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461545(CHEMBL4226876)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HCV NS3/4a protease using Ac-DE-Dap(QXL520)-EE-Abu-shi-[COO]AS-C(5-FAMsp)-NH2 as substrate after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461549(CHEMBL4225009)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461552(CHEMBL4228791)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461537(CHEMBL4228440)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461556(CHEMBL4225149)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461547(CHEMBL4225051)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461555(CHEMBL4225768)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461554(CHEMBL4225514)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461539(CHEMBL4229110)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461551(CHEMBL4229052)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461542(CHEMBL4224705)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461541(CHEMBL4225301)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461564(CHEMBL4228533)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50287594(Asunaprevir | BMS 650032 | BMS-650032)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50287594(Asunaprevir | BMS 650032 | BMS-650032)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50287622(CHEMBL4160876)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461562(CHEMBL4227396)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461565(CHEMBL4228402)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50110122((S)-4-((S)-2-Acetylamino-3-carboxy-propionylamino)...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50122900(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461550(CHEMBL2403888)
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461553(CHEMBL4228282)
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of HCV NS3/4a protease using Ac-DE-Dap(QXL520)-EE-Abu-shi-[COO]AS-C(5-FAMsp)-NH2 as substrate after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461543(CHEMBL4229158)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461538(CHEMBL4227401)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461535(CHEMBL4226548)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461546(CHEMBL4225716)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50537589(CHEMBL4287268)
Affinity DataIC50: 3nMAssay Description:Inhibition of HCV NS3/4a protease using Ac-DE-Dap(QXL520)-EE-Abu-shi-[COO]AS-C(5-FAMsp)-NH2 as substrate after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461558(CHEMBL4227183)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 2b NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461536(CHEMBL4225561)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50122902(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096729((S)-4-((S)-1-{(S)-1-[(S)-1-((R)-1-Benzylaminooxaly...)
Affinity DataIC50: 4nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096726(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50: 4nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096734((S)-4-[(S)-3-Carboxy-2-(3-carboxy-propionylamino)-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096730(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50: 4nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461557(CHEMBL414993)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461548(CHEMBL4224849)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461534(CHEMBL4226979)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50287595(CHEMBL3921126)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096727((S)-4-[(S)-3-Carboxy-2-(3-carboxy-propionylamino)-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50287648(CHEMBL3895075)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50122897(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096725(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50: 7nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096733(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50: 7nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096728((S)-4-((S)-1-{(S)-1-[(S)-1-((S)-1-Amino-2-carbamoy...)
Affinity DataIC50: 7nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461548(CHEMBL4224849)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 2b NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461548(CHEMBL4224849)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 3a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50096732(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50: 8nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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