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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50482166(3-Iodocytisine | CHEMBL187394)
Affinity DataIC50: 0.245nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170589((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50329578((-)-9-Bromocytisine | (1R,5S)-9-Bromo-1,2,3,4,5,6-...)
Affinity DataIC50: 0.309nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187442(1-(6-bromo-5-vinyloxypyridin-3-yl)-[1,5]-diazocane...)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187445(1-(6-bromopyridin-3-yl)-[1,5]-diazocane | 1-(6-bro...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187455(1-(6-Bromo-5-vinylpyridin-3-yl)-[1,4]diazepane | 1...)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50088456(1-(6-Chloro-5-methoxy-pyridin-3-yl)-[1,4]diazepane...)
Affinity DataIC50: 0.680nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170586((3S)-3-{[(2S)-1-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2...)
Affinity DataIC50: 0.75nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta2; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170586((3S)-3-{[(2S)-1-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2...)
Affinity DataIC50: 0.75nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta2; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50088453(CHEMBL72433 | NS3570, 5 | 1-(6-bromo-5-ethoxypyrid...)
Affinity DataIC50: 0.870nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187447(1-(pyridin-3-yl)-1,5-diazocane | 1-pyridin-3-yl-[1...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50078044(3-(6-Chloro-pyridin-3-ylmethyl)-3H-thiazol-2-ylide...)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50548705(CHEMBL4740159)
Affinity DataIC50: 0.960nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by radioligand competition analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50088454(NS3920, 4 | CHEMBL306387 | 1-(6-bromopyridin-3-yl)...)
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187439(1-(5-Methoxypyridin-3-yl)-[1,5]diazocane | 1-(5-me...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50140089(GCCSHPACAGNNQHIC* | CHEMBL437423)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of alpha-4-beta-2 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187438(cis-1-(5-propen-1-yloxypyridin-3-yl)-[1,4]diazepan...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187453(1-(6-bromo-5-chloropyridin-3-yl)-[1,4]-diazepane |...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187441(4-(5-bromo-6-chloropyridin-3-yl)-[1,4]-diazepane |...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170592(CHEMBL411146)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta2; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50475830(CHEMBL210643)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50475827(CHEMBL206988)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50078056(2-Chloro-5-(1-methyl-pyrrolidin-2-yl)-pyridine | C...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187437(1-(5-chloropyridin-3-yl)-1,5-diazocane | 1-(5-chlo...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50472282(descyanothiacloprid)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50329473((S)-N-(1-(3-(4-(3-aminopropylamino)butylamino)prop...)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at alpha4beta2 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50187454(1-(5-bromopyridin-3-yl)-1,5-diazocane | 1-(5-Bromo...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50472297(CHEMBL308637)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50475829(CHEMBL378629)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50475824(CHEMBL382049)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50472290(CHEMBL440307)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50548704(CHEMBL4791046)
Affinity DataIC50: 3.90nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by radioligand competition analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50433566(CHEMBL2381566)
Affinity DataIC50: 4.20nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50382474(CHEMBL2024096 | US9303017, Sazetidine-A)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in SH-EP1 cells assessed as inhibition of carbamylcholine induced 86Rb+ ion efflux preincuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50548703(CHEMBL4793576)
Affinity DataIC50: 4.80nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by radioligand competition analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50: 4.90nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by radioligand competition analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170584(CHEMBL411145)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta2; Range is 3-5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50088450(1-(5-Vinyloxy-pyridin-3-yl)-[1,4]diazepane | 1-(5-...)
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 (alpha4 beta-2 subtype of nAChRs) in rat cerebral cortical membrane using...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50515189(CHEMBL4463134)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at alpha4beta2 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50437504(CHEMBL2409631)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human alpha4beta2 nACHR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux prei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50382472(CHEMBL2024094)
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at human alpha4beta2 nACHR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux prei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50382472(CHEMBL2024094)
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in SH-EP1 cells assessed as inhibition of carbamylcholine induced 86Rb+ ion efflux preincuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50475828(CHEMBL208630)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50078048(1-(6-Chloro-pyridin-3-ylmethyl)-imidazolidin-(2Z)-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50475823(CHEMBL207038)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Instituto De Investigaciones Biol£Gicas Clemente Estable

Curated by ChEMBL
LigandPNGBDBM50472292(CHEMBL309577)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50382474(CHEMBL2024096 | US9303017, Sazetidine-A)
Affinity DataIC50: 7.5nMAssay Description:IC50(10′): The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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