BDBM50004051 2-Amino-4-phosphono-butyric acid::2-Amino-4-phosphono-butyric acid (AP4)::4-Amino Phosphonobutyrate::CHEMBL285843::GlcN-6-P synthase inhibitor, 1 (racemic mixture)::L-AP4

SMILES C(CP(=O)(O)O)[C@@H](C(=O)O)N

InChI Key InChIKey=DDOQBQRIEWHWBT-UHFFFAOYSA-N

Data  14 KI  2 IC50  3 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004051   

TargetMetabotropic glutamate receptor 8(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004051(CHEMBL285843 | 2-Amino-4-phosphono-butyric acid | ...)
Affinity DataIC50: 5.10nMAssay Description:Inhibitory concentration against [3H]1 binding to recombinant human Metabotropic glutamate receptor 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 8(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004051(CHEMBL285843 | 2-Amino-4-phosphono-butyric acid | ...)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 8(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(CHEMBL285843 | 2-Amino-4-phosphono-butyric acid | ...)
Affinity DataKi:  1.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)