BDBM50282632 3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1H-2,4a-diaza-cyclopenta[b]fluoren-9-yl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione; hydrochloride::CHEMBL538718::Ro-32-0557

SMILES CN1C[C@@H]2Cc3c(C4=C(C(=O)NC4=O)c4cn(C)c5ccccc45)c4ccccc4n3C[C@H]2C1

InChI Key InChIKey=SAYMBMAHSBYKKR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50282632   

TargetProtein kinase C beta type(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(Ro-32-0557 | 3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C gamma type(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(Ro-32-0557 | 3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of Protein kinase C gamma (PKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(Ro-32-0557 | 3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Protein kinase C betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C alpha type(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(Ro-32-0557 | 3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10...)
Affinity DataIC50: 2.85nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C epsilon type(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(Ro-32-0557 | 3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10...)
Affinity DataIC50: 48nMAssay Description:Inhibition of Protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article