BDBM50017656 CHEMBL1193::Dimethyl-(3-phenyl-3-pyridin-2-yl-propyl)-amine::Naphcon-A::Opcon-A::PHENIRAMINE::Visine-A

SMILES CN(C)CCC(c1ccccc1)c1ccccn1

InChI Key InChIKey=IJHNSHDBIRRJRN-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017656   

LigandPNGBDBM50017656(Visine-A | Dimethyl-(3-phenyl-3-pyridin-2-yl-propy...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50017656(Visine-A | Dimethyl-(3-phenyl-3-pyridin-2-yl-propy...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50017656(Visine-A | Dimethyl-(3-phenyl-3-pyridin-2-yl-propy...)
Affinity DataEC50:  2.82E+4nMAssay Description:Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 5 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
The Centre For Addiction and Mental Health

Curated by PDSP Ki Database
LigandPNGBDBM50017656(Visine-A | Dimethyl-(3-phenyl-3-pyridin-2-yl-propy...)
Affinity DataKi:  4.18E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2012
Entry Details Article
PubMed