BDBM50303149 (-)-licarin A::CHEMBL463526::Licarin A

SMILES COc1cc(\C=C\C)cc2[C@H](C)[C@H](Oc12)c1ccc(O)c(OC)c1

InChI Key InChIKey=ITDOFWOJEDZPCF-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303149   

TargetProstaglandin G/H synthase 1(Sheep)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50303149(Licarin A | (-)-licarin A | CHEMBL463526)
Affinity DataIC50: 3.12E+5nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50303149(Licarin A | (-)-licarin A | CHEMBL463526)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303149(Licarin A | (-)-licarin A | CHEMBL463526)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303149(Licarin A | (-)-licarin A | CHEMBL463526)
Affinity DataKi:  9.40E+3nMAssay Description:Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed