BDBM50031282 CHEBI:17630::Kanamycin

SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key InChIKey=SBUJHOSQTJFQJX-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50031282   

Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
School of Life Science Nanjing University

Curated by ChEMBL
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of Escherichia coli FabHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 1.10E+5nMAssay Description:In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details Article
PubMed
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetGap junction beta-2 protein(Human)
Utah State University

Curated by ChEMBL
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of recombinant human Cx26 expressed in Escherichia coli LB2003 assessed as reduction in cell growth measured after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhospholipase A1 member A(Rat)
Agricultural University of Athens

Curated by ChEMBL
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 8.04E+4nMAssay Description:IC50 was measured as concentration causing 50% inhibition of lysosomal phospholipase A1 activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetGap junction alpha-1 protein(Human)
Utah State University

Curated by ChEMBL
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human Cx43 expressed in Escherichia coli LB2003 cells in medium containing 8 mM K+ and 10 uM IPTG by measuring cell growth after 18 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetGap junction beta-2 protein(Human)
Utah State University

Curated by ChEMBL
LigandPNGBDBM50031282(CHEBI:17630 | Kanamycin)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human Cx26 expressed in Escherichia coli LB2003 cells in medium containing 4 mM K+ and 500 uM IPTG by measuring cell growth after 18 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed