BDBM217352 GS-9820

SMILES C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2c(=O)n1-c1ccccc1

InChI Key InChIKey=DOCINCLJNAXZQF-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 217352   

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 5.44E+3nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 3.38E+3nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 1.39E+3nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 12.7nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 1.00E+4nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 1.00E+4nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Mouse)
Western University

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 1.87E+4nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Mouse)
Western University

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 1.00E+5nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GST-tagged PI3Kgamma (unknown origin) using PIP2 as substrate preincubated for 2 hrs followed by ATP addition measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3K-delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed