BDBM50131281 5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamino)ethyl)benzene-1,3-diol::5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol::CHEMBL32800::FENOTEROL

SMILES C[C@@H](Cc1ccc(cc1)O)NC[C@H](c2cc(cc(c2)O)O)O

InChI Key InChIKey=LSLYOANBFKQKPT-UHFFFAOYSA-N

Data  6 KI  2 IC50  1 Kd  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50131281   

TargetBeta-2 adrenergic receptor(Guinea pig)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory concentration Beta-2 adrenergic receptor in Guinea pig tracheaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataKd:  100nMAssay Description:Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataKi:  490nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataKi:  513nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataKi:  719nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Guinea pig)
Ohio State University

Curated by PDSP Ki Database
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataKi:  4.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Human)
UniversitÄT WÜRzburg

Curated by PDSP Ki Database
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
UniversitÄT WÜRzburg

Curated by PDSP Ki Database
LigandPNGBDBM50131281(5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamin...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed