BDBM50079903 7-Methoxy-4,9-dihydro-3H-beta-carboline::CGS-19281A::CHEMBL6409

SMILES COc1ccc2c3CCN=Cc3[nH]c2c1

InChI Key InChIKey=VTEZDUSEJVSZGQ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50079903   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079903(CGS-19281A | 7-Methoxy-4,9-dihydro-3H-beta-carboli...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of PNMT (Phenylethanolamine N-Methyltransferase) in vitro More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079903(CGS-19281A | 7-Methoxy-4,9-dihydro-3H-beta-carboli...)
Affinity DataKi:  2.70E+3nMAssay Description:Affinity for bovine Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079903(CGS-19281A | 7-Methoxy-4,9-dihydro-3H-beta-carboli...)
Affinity DataKi:  2.70E+3nMAssay Description:Ability to inhibit phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50079903(CGS-19281A | 7-Methoxy-4,9-dihydro-3H-beta-carboli...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 5A receptor using LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50079903(CGS-19281A | 7-Methoxy-4,9-dihydro-3H-beta-carboli...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for rat 5-hydroxytryptamine 2A receptor using [3H]DOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50079903(CGS-19281A | 7-Methoxy-4,9-dihydro-3H-beta-carboli...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards cloned rat 5-hydroxytryptamine 2C receptor from fundus tissue by [3H]mesulergine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50079903(CGS-19281A | 7-Methoxy-4,9-dihydro-3H-beta-carboli...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards cloned rat 5-hydroxytryptamine 2A receptor by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50079903(CGS-19281A | 7-Methoxy-4,9-dihydro-3H-beta-carboli...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at alpha-2 adrenergic receptors of rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed