BDBM90654 2-[5-(3-Nitro-phenyl)-[1,2,4]oxadiazol-3-yl]-pyridine::5-(3-nitrophenyl)-3-(2-pyridinyl)-1,2,4-oxadiazole::5-(3-nitrophenyl)-3-(2-pyridyl)-1,2,4-oxadiazole::5-(3-nitrophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole::MLS001012185::SMR000425198::cid_867096

SMILES [O-][N+](=O)c1cccc(c1)-c1nc(no1)-c1ccccn1

InChI Key InChIKey=YYKRPCBJFTUNFZ-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 90654   

TargetCorticotropin-releasing factor-binding protein(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM90654(MLS001012185 | 2-[5-(3-Nitro-phenyl)-[1,2,4]oxadia...)
Affinity DataEC50: >5.30E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetOxysterols receptor LXR-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM90654(MLS001012185 | 2-[5-(3-Nitro-phenyl)-[1,2,4]oxadia...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM90654(MLS001012185 | 2-[5-(3-Nitro-phenyl)-[1,2,4]oxadia...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM90654(MLS001012185 | 2-[5-(3-Nitro-phenyl)-[1,2,4]oxadia...)
Affinity DataIC50: 236nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed