BDBM674468 N-(2-(6-fluoro-7-methoxy-naphthalen-1-yl)ethyl)acetamide::US11980598, Compound 4

SMILES COc1cc2c(CCNC(C)=O)cccc2cc1F

InChI Key InChIKey=DILUDKYRTBFGTR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 674468   

TargetMelatonin receptor type 1A(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674468(N-(2-(6-fluoro-7-methoxy-naphthalen-1-yl)ethyl)ace...)
Affinity DataIC50: 0.230nMAssay Description:The test tubes were placed in a reaction condition of 25° C. 10 μL of receptor membrane protein MT1 or MT2 was added to all the tubes. In non-sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
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TargetMelatonin receptor type 1B(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674468(N-(2-(6-fluoro-7-methoxy-naphthalen-1-yl)ethyl)ace...)
Affinity DataIC50: 0.670nMAssay Description:The test tubes were placed in a reaction condition of 25° C. 10 μL of receptor membrane protein MT1 or MT2 was added to all the tubes. In non-sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Beijing Greatway Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM674468(N-(2-(6-fluoro-7-methoxy-naphthalen-1-yl)ethyl)ace...)
Affinity DataIC50: 20.8nMAssay Description:The test tubes were placed under a reaction condition of 25° C. 50 μg of the receptor membrane protein 5-HT2C was added to all the tubes. In non...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
Go to US Patent