BDBM659306 US20240092759, Compound 30

SMILES COc1cc(CCOc2cc(Cl)cc(c2)-c2cc(cn(-c3cccnc3)c2=O)-c2ccccc2C#N)cc(OC)c1

InChI Key InChIKey=VFEZCYFYPXBRBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659306   

TargetReplicase polyprotein 1a(2019-nCoV)
Yale University

US Patent
LigandPNGBDBM659306(US20240092759, Compound 30)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-Cov-2 Mpro, as described herein in the Experimental section. For the kinetic ass...More data for this Ligand-Target Pair
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Date in BDB:
6/4/2024
Entry Details
Go to US Patent