BDBM637504 (3-amino-6-(pyrrolidin-1-yl)-1H- pyrazolo[3,4-d]pyrimidin-1-yl)(2- methoxyphenyl)methanone::US20230382911, Example 16

SMILES COc1ccccc1C(=O)n1nc(N)c2cnc(nc12)N1CCCC1

InChI Key InChIKey=CTYHCRCDVSNZFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637504   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637504(US20230382911, Example 16 | (3-amino-6-(pyrrolidin...)
Affinity DataIC50: 65nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent