BDBM594030 Synthesis of 2-((R,6E,10E)-3-hydroxy-3,7, 11-trimethyl-14-(oxetan-3-ylidene)tetradeca-6,10-dien-1-yl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione ::US11584728, Compound E::US12049455, Compound E

SMILES [#6]\[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6]-1/[#6]-[#8]-[#6]-1)=[#6]/[#6]-[#6][C@@]([#6])([#8])[#6]-[#6]-[#6]-1=[#6](-[#6])-[#6](=O)-[#6](-[#6])=[#6](-[#6])-[#6]-1=O

InChI Key InChIKey=RWXJUKHNJZTPBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594030   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594030(US11584728, Compound E | Synthesis of 2-((R,6E,10E...)
Affinity DataIC50: 1.00E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594030(US11584728, Compound E | Synthesis of 2-((R,6E,10E...)
Affinity DataIC50: 10nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent