BDBM590003 (S)-1-(4-(6-amino-5- (trifluoromethyl)pyridin-3-yl)-1- (bicyclo[1.1.1]pentan-1-yl)-1H-imidazol- 2-yl)-2-methylpropan-1-ol::US11560366, Example 14b

SMILES CC(C)[C@H](O)c1nc(cn1C12CC(C1)C2)-c1cnc(N)c(c1)C(F)(F)F

InChI Key InChIKey=ZNLWKSRHKZKBQH-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 590003   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
University Of Texas

US Patent
LigandPNGBDBM590003((S)-1-(4-(6-amino-5- (trifluoromethyl)pyridin-3-yl...)
Affinity DataKd:  0.120nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
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TargetProtein delta homolog 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM590003((S)-1-(4-(6-amino-5- (trifluoromethyl)pyridin-3-yl...)
Affinity DataKi:  15nMAssay Description:Binding affinity to DLK (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed