BDBM50630232 CHEMBL5433617

SMILES Cn1cncc1C2=CN(CCS2)c3c4c([nH]cn4)ncn3

InChI Key InChIKey=IEDDDZFQZKDRBJ-UHFFFAOYSA-N

Data  11 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50630232   

TargetcGMP-dependent protein kinase 1(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 11nMAssay Description:Inhibition of PKG1 alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetcGMP-dependent protein kinase 1(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 15nMAssay Description:Inhibition of PKG1 beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetcGMP-dependent protein kinase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 34nMAssay Description:Inhibition of PKG2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetSTE20/SPS1-related proline-alanine-rich protein kinase(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 35nMAssay Description:Inhibition of STLK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 36nMAssay Description:Inhibition of PKC theta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase LATS1(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 64nMAssay Description:Inhibition of LATS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase LATS2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 70nMAssay Description:Inhibition of LATS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 64nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 71nMAssay Description:Inhibition of CLK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 84nMAssay Description:Inhibition of PKAc alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630232(CHEMBL5433617)
Affinity DataIC50: 970nMAssay Description:Inhibition of wild type PKAc alpha (unknown origin) using CREB KRREILSRRPSYR-biotinylated peptide as substrate incubated for 45 mins in presence of A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)