BDBM50629789 CHEMBL5401656

SMILES COc1ccc(cc1C#N)S(=O)(=O)N(C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(C#Cc2ccccc2)c2c(N)ncnc12

InChI Key InChIKey=VJJHEKWIBTUWDR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629789   

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50629789(CHEMBL5401656)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50629789(CHEMBL5401656)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50629789(CHEMBL5401656)
Affinity DataIC50: 5.65E+4nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed