BDBM50616996 CHEMBL5416465

SMILES Nc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(=O)C(F)F

InChI Key InChIKey=SSJLVEWXIPHBTF-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50616996   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50616996(CHEMBL5416465)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human GluN2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50616996(CHEMBL5416465)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GluN2A receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50616996(CHEMBL5416465)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GluN2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50616996(CHEMBL5416465)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GluN2D receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50616996(CHEMBL5416465)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50616996(CHEMBL5416465)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to rat GluN2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed