BDBM50603869 CHEMBL5194984

SMILES [O-]P(=O)(OC1=Cc2ccccc2Sc2ccccc12)OC1=Cc2ccccc2Sc2ccccc12

InChI Key InChIKey=YHPSLTOOUSTOBR-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50603869   

TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603869(CHEMBL5194984)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in 6-OAU induced intracellular calcium resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603869(CHEMBL5194984)
Affinity DataIC50: 118nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in 3-OH-C12 induced intracellular calcium r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603869(CHEMBL5194984)
Affinity DataIC50: 413nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells assessed as reversal of 6-OAU induced inhibition of forskolin induced intracellular cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603869(CHEMBL5194984)
Affinity DataIC50: 454nMAssay Description:Antagonist activity at mouse GPR84 expressed in HEK293 cells assessed as reduction in 6-OAU induced intracellular calcium response preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed