BDBM50603799 CHEMBL5180152

SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CSCc2ccc(CSC[C@H](NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](Cc3c[nH]cn3)NC1=O)C(N)=O)cc2

InChI Key InChIKey=UYOAPGITMAMCFT-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50603799   

TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataIC50: 7.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataEC50:  645nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603799(CHEMBL5180152)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed