BDBM50590381 CHEMBL5173402

SMILES CC(c1ccccc1)n1nc(NC(=O)C=C)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C

InChI Key InChIKey=WLAGRCJKPUFIOP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50590381   

TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590381(CHEMBL5173402)
Affinity DataIC50: 64nMAssay Description:Inhibition of EZH2 (494 to 737 residues) (unknown origin) expressed in Escherichia coli by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590381(CHEMBL5173402)
Affinity DataIC50: 64nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590381(CHEMBL5173402)
Affinity DataIC50: 64nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590381(CHEMBL5173402)
Affinity DataIC50: 64nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed