BDBM50587753 CHEMBL5190569

SMILES COc1cc(\C=C\c2nnc(o2)-c2ccc(cc2)C(F)(F)F)ccc1O

InChI Key InChIKey=JYQOQNLXJDCXHD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50587753   

TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50: 68nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate by Ellman colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50: 255nMAssay Description:Inhibition of human BuchE using butyrylthiocholine iodide as substrate by Ellman colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50: 255nMAssay Description:Inhibition of human BACE-1 by FRET-based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50: 0.255nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed