BDBM50563094 CHEMBL4753913

SMILES COc1ccc(\C=C2\N=C(N(NC2=O)C(=O)Cc2nc3n(nc(C)c3c(=O)[nH]2)-c2ccccc2)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=GGKMDRBWPANQRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563094   

TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50563094(CHEMBL4753913)
Affinity DataIC50: 227nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50563094(CHEMBL4753913)
Affinity DataIC50: 866nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed