BDBM50562510 CHEMBL4749491

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1NCCNC(=O)Cc1cccc(c1)N(CCCl)CCCl

InChI Key InChIKey=QGNKAWRJOHQHFT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562510   

TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562510(CHEMBL4749491)
Affinity DataIC50: 130nMAssay Description:Inhibition of human IDO1 using D-Trp as substrate by absorbance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562510(CHEMBL4749491)
Affinity DataEC50:  270nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as effect on kynurenine level incubated for 48 hrs by p-dimethylaminobenzaldehyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed