BDBM50560737 CHEMBL4783301

SMILES CC(C)N1[C@H](C)C(=O)N(C)c2ccc(Nc3ncc(Cl)c(n3)-c3cncc4ccccc34)cc12

InChI Key InChIKey=XSORNHYQCJBFAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560737   

TargetBromodomain-containing protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50560737(CHEMBL4783301)
Affinity DataIC50: 58nMAssay Description:Inhibition of His6-tagged BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) cells incubated for 4 hrs by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50560737(CHEMBL4783301)
Affinity DataIC50: 23nMAssay Description:Inhibition of human CDK9 by mobility shift assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed