BDBM50560725 CHEMBL4745398

SMILES CC(C)Nc1cccc(c1)-c1ccnc(Nc2ccc3N(C)C(=O)[C@@H](C)N(C(C)C)c3c2)n1

InChI Key InChIKey=PTQOCRSAANWGGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560725   

TargetBromodomain-containing protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50560725(CHEMBL4745398)
Affinity DataIC50: 268nMAssay Description:Inhibition of His6-tagged BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) cells incubated for 4 hrs by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50560725(CHEMBL4745398)
Affinity DataIC50: 51nMAssay Description:Inhibition of human CDK9 by mobility shift assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed