BDBM50552414 CHEMBL4791592

SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1O)c1cc(F)cc(F)c1

InChI Key InChIKey=RJQVGHLPISEKIW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552414   

LigandPNGBDBM50552414(CHEMBL4791592)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50552414(CHEMBL4791592)
Affinity DataEC50:  1.20E+4nMAssay Description:Activation of human PXR ligand binding domain incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed