BDBM50550710 CHEMBL4749782

SMILES COc1cc(ccc1CNCCO)C(=O)N1CCc2c1cccc2-c1ccccc1

InChI Key InChIKey=SBBYNJFHJDJZJK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50550710   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550710(CHEMBL4749782)
Affinity DataIC50: 133nMAssay Description:Inhibition of PD-1/PDL1 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550710(CHEMBL4749782)
Affinity DataIC50: 133nMAssay Description:Inhibition of PD1 (unknown origin)/PDL1 (unknown origin) protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550710(CHEMBL4749782)
Affinity DataIC50: 152nMAssay Description:Inhibition of PD1/PD-L1 (unknown origin) protein-protein interaction measured after 135 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50550710(CHEMBL4749782)
Affinity DataIC50: 161nMAssay Description:Inhibition of Tag2-PD1/Tag1-PD-L1 (unknown origin) protein-protein interaction preincubated for 15 mins followed by addition of anti-Tag1-Eu3+ and an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50550710(CHEMBL4749782)
Affinity DataIC50: 133nMAssay Description:Inhibition of PD-1 (unknown origin)/PD-L1 (unknown origin) interaction by HTRF binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed