BDBM50537906 CHEMBL4646024

SMILES [H][C@]12CN([C@@H](Cc3cc4OCOc4c(OC)c3)CN1C(=O)[C@@]1(O[C@H]1c1ccccc1)[C@@H]2c1cc2OCOc2c(OC)c1)C(C)=O

InChI Key InChIKey=IKMTWSYMQMGXCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537906   

TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50537906(CHEMBL4646024)
Affinity DataIC50: 3.00E+4nMAssay Description:Reversal of P-gp mediated multidrug resistance in human SW620/AD300 cells assessed as potentiation of doxorubicin-induced antiproliferative activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50537906(CHEMBL4646024)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of P-glycoprotein overexpressed in human SW620/AD300 cells assessed as reversal of doxorubicin resistance by measuring doxorubicin IC50 at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed