BDBM50530429 CHEMBL4575900

SMILES C[C@H](Cn1c(C)nc2ccc(nc12)-c1cc(N)nc(N)c1)Oc1ccccc1

InChI Key InChIKey=PUGXENIKUPHCAF-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50530429   

LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 8nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 12nMAssay Description:Inhibition of DYRK1A (unknown origin) by ADP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 8nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 12nMAssay Description:Inhibition of DYRK1A (unknown origin) by ADP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 19nMAssay Description:Inhibition of CLK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 19nMAssay Description:Inhibition of CLK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 8nMAssay Description:Inhibition of DYRK1A (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 46nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50530429(CHEMBL4575900)
Affinity DataIC50: 111nMAssay Description:Inhibition of wild type full length DYRK1A (unknown origin) in human U2OS cells assessed as reduction in pSER520 autophosphorylation incubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed