BDBM50520467 CHEMBL4482942

SMILES CCOc1ccc(CN2CCCCC2)cc1CNC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C

InChI Key InChIKey=YIOASLYSFGWMAA-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50520467   

TargetMu-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50520467(CHEMBL4482942)
Affinity DataEC50:  585nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50520467(CHEMBL4482942)
Affinity DataEC50:  129nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50520467(CHEMBL4482942)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in CHO cell membranes incubated for 1 hr by liquid scintillation counting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50520467(CHEMBL4482942)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in CHO cell membranes incubated for 1 hr by liquid scintillation counting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50520467(CHEMBL4482942)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in CHO cell membranes incubated for 1 hr by liquid scintillation counting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed