BDBM50519964 CHEMBL4461596

SMILES COc1ccc(cc1)[C@H]([S@+]([O-])Cc1cncs1)c1ccccc1

InChI Key InChIKey=ZIRUMFOISHAJDS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50519964   

TargetSodium-dependent dopamine transporter(Human)
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50519964(CHEMBL4461596)
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of wild type human dopamine transporter expressed in HEK293 cells assessed as inhibition of [3H]dopamine reuptake preincubated for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50519964(CHEMBL4461596)
Affinity DataIC50: 2.61E+5nMAssay Description:Inhibition of wild type human NET expressed in HEK293 cells assessed as inhibition of [3H]-MPP+ reuptake preincubated for 5 mins followed by [3H]MPP+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50519964(CHEMBL4461596)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 cells assessed as inhibition of [3H]-5HT reuptake preincubated for 5 mins followed by [3H]5HT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed