BDBM50514853 CHEMBL4557734

SMILES CN1CCc2c(C1)nnn2CC(=O)Nc1ccc(Br)c(c1)S(=O)(=O)N1CC[C@H](C1)C1CC1

InChI Key InChIKey=QFRIGJQJVRCBFQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514853   

TargetChromatin remodeling regulator CECR2(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50514853(CHEMBL4557734)
Affinity DataIC50: 40nMAssay Description:Displacement of Alexa Fluor 647-labeled GSK tracer from FLAG-6His-Tev-fused CECR2 (424 to 543 residue) (unknown origin) measured after 15 mins by TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50514853(CHEMBL4557734)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of Alexa Fluor 488-labeled ligand from FLAG-6His-Tev-fused ATAD2 (981 to 1121 residue) (unknown origin) measured after 30 mins by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50514853(CHEMBL4557734)
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of Alexa Fluor 647-labeled ligand from BRD4 BD1 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed