BDBM50505870 CHEMBL4531775

SMILES FC(F)(F)c1c(cnn1-c1ccccc1)C(=O)NCc1ccc(cc1)C(=O)NCCCC1CCCCC1

InChI Key InChIKey=HMPXSYOFBMBHDF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50505870   

TargetMitogen-activated protein kinase kinase kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505870(CHEMBL4531775)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of ZAK (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505870(CHEMBL4531775)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KIT (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505870(CHEMBL4531775)
Affinity DataIC50: 220nMAssay Description:Inhibition of DDR2 (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMyosin light chain kinase family member 4(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505870(CHEMBL4531775)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MYLK4 (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-6(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505870(CHEMBL4531775)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of RSK4 kinase domain 1 (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505870(CHEMBL4531775)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of full-length human C-terminal NanoLuc-tagged P38 alpha MAPK expressed in human HEK293T cells incubated for 2 hrs followed by NanoBRET Na...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505870(CHEMBL4531775)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of DDR1 (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505870(CHEMBL4531775)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of p38-beta (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed