BDBM50469400 CHEMBL4278109

SMILES CCCc1nc2c(cccc2n1Cc3ccc\4c(c3)COc5ccccc5/C4=C(\C)/C6=NOC(=O)N6)C

InChI Key InChIKey=KWALRLFFHWLMRU-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469400   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Fuji Research Park, R&D Division

Curated by ChEMBL
LigandPNGBDBM50469400(CHEMBL4278109)
Affinity DataEC50:  2.40nMAssay Description:Transactivation of GAL4-fused human PPARgamma transfected in HEK293BENA cells after 24 hrs by steady glo-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Fuji Research Park, R&D Division

Curated by ChEMBL
LigandPNGBDBM50469400(CHEMBL4278109)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at PPARgamma in human MKN45 cells assessed as induction of cell aggregation incubated for 5 days by Hoechst 33342 staining based IN ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)